Difference between revisions of "FsrA"
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs and inhibits their translation. | + | * '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[sdhC]], [[citB]], [[lutB]], [[gltA]]-[[gltB]]'', and ''[[leuC]]-[[leuD]]'' mRNAs and inhibits their translation. {{PubMed|18697947,22389480}} |
=== Extended information on the RNA=== | === Extended information on the RNA=== | ||
Line 78: | Line 78: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
− | ** Binds ''[[sdhC]], [[citB]], [[lutB]], and [[leuC]]-[[leuD]]'' mRNAs | + | ** Binds ''[[sdhC]], [[citB]], [[lutB]], [[gltA]]-[[gltB]]'', and ''[[leuC]]-[[leuD]]'' mRNAs {{PubMed|18697947,22389480}} |
* '''[[Localization]]''' | * '''[[Localization]]''' |
Revision as of 17:45, 14 March 2012
- Description: regulatory RNA
Gene name | fsrA |
Synonyms | |
Essential | no |
Product | sRNA FsrA |
Function | inhibition of sdhC translation |
Gene length | aaa bp |
Immediate neighbours | ykuI, ykuJ |
Gene sequence (+200bp) | |
Genetic context |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The FsrA regulon
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: no entry
- Structure:
Additional information
- Swiss prot entry:
- KEGG entry: no entry
- E.C. number:
Additional information
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to sdhC, citB, lutB, gltA-gltB, and leuC-leuD mRNAs and inhibits their translation. PubMed
Extended information on the RNA
- Kinetic information
Database entries
- Structure:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
Labs working on this gene/RNA
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Gregory T Smaldone, Olga Revelles, Ahmed Gaballa, Uwe Sauer, Haike Antelmann, John D Helmann
A global investigation of the Bacillus subtilis iron-sparing response identifies major changes in metabolism.
J Bacteriol: 2012, 194(10);2594-605
[PubMed:22389480]
[WorldCat.org]
[DOI]
(I p)
Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947]
[WorldCat.org]
[DOI]
(I p)