Difference between revisions of "RNA polymerase"

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(Other temporary components)
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===Other temporary components===
 
===Other temporary components===
 
* [[NusA]]: essential elongation factor
 
* [[NusA]]: essential elongation factor
 +
* [[Spx]]: transcription regulator, interacts with [[RpoA]]
 +
* [[MgsR]]: transcription regulator orthologous to [[Spx]], interacts with [[RpoA]]
  
 
==Back to [[protein-protein interactions]]==
 
==Back to [[protein-protein interactions]]==

Revision as of 14:11, 8 April 2011

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The enzyme responsible for transcription

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • YloH: omega subunit

Other temporary components

  • NusA: essential elongation factor
  • Spx: transcription regulator, interacts with RpoA
  • MgsR: transcription regulator orthologous to Spx, interacts with RpoA

Back to protein-protein interactions

References

Reviews

The structure of RNA polymerase

Important original publications: PubMed

Houra Merrikh, Cristina Machón, William H Grainger, Alan D Grossman, Panos Soultanas
Co-directional replication-transcription conflicts lead to replication restart.
Nature: 2011, 470(7335);554-7
[PubMed:21350489] [WorldCat.org] [DOI] (I p)