Difference between revisions of "SwrAA/1"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[biofilm formation]]}}, | ||
{{SubtiWiki category|[[motility and chemotaxis]]}}, | {{SubtiWiki category|[[motility and chemotaxis]]}}, | ||
{{SubtiWiki category|[[pseudogenes]]}} | {{SubtiWiki category|[[pseudogenes]]}} | ||
| Line 55: | Line 56: | ||
=== Additional information=== | === Additional information=== | ||
| − | This protein is functional in undomesticated strains of ''B.subtilis'' but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of ''B.subtilis'' are unable to swarm. | + | * This protein is functional in undomesticated strains of ''B.subtilis'' but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of ''B.subtilis'' are unable to swarm. |
| − | + | * The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of ''swrAA'' was predicted to be an ORF (''[[yvzD]]'') by the genome project. | |
| − | The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of ''swrAA'' was predicted to be an ORF (''[[yvzD]]'') by the genome project. | + | * Correction of ''[[sfp]]'', ''[[epsC]]'','' [[swrAA]]'', and ''[[degQ]]'' as well as introduction of ''rapP'' from a plasmid present in NCIB3610 results in biofilm formation in ''B. subtilis'' 168 {{PubMed|21278284}} |
| − | |||
| Line 134: | Line 134: | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>16357223,19389763,16030230,18567663,15066026,, 19389763 19749039 </pubmed> | + | <pubmed>16357223,19389763,16030230,18567663,15066026,, 19389763 19749039 21278284 </pubmed> |
[[Category:Pseudogenes]] | [[Category:Pseudogenes]] | ||
Revision as of 10:17, 1 February 2011
- Description: control of motility, enhances sigD transcription
| Gene name | swrA |
| Synonyms | yvzD, swrAA, ifm |
| Essential | no |
| Product | swarming motility protein |
| Function | essential for swarming differentiation on solid surfaces |
| MW, pI | 13 kDa, 8.4 |
| Gene length, protein length | 336 bp, 112 aa |
| Immediate neighbours | minJ, ctpB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biofilm formation, motility and chemotaxis, pseudogenes
This gene is a member of the following regulons
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
- This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm.
- The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.
- Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: O32266
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
