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− | ''' | + | * '''Description:''' amino acid racemase, production of D-amino acids, control of [[biofilm formation]] <br/><br/> |
− | = [[ | + | {| align="right" border="1" cellpadding="2" |
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
+ | |''racX'' | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"| '''Product''' || amino acid racemase | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[biofilm formation]] | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.396 | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 681 bp, 227 aa | ||
+ | |- | ||
+ | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yveF]]'', ''[[pbpE]]'' | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15448]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
+ | |- | ||
+ | |colspan="2" | '''Genetic context''' <br/> [[Image:racX_context.gif]] | ||
+ | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |} | ||
− | + | __TOC__ | |
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− | + | <br/><br/> | |
− | + | = [[Categories]] containing this gene/protein = | |
− | + | {{SubtiWiki category|[[biofilm formation]]}}, | |
− | + | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, W, X, Y)]]}} | |
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− | = [[ | + | = This gene is a member of the following [[regulons]] = |
+ | {{SubtiWiki regulon|[[AbrB regulon]]}}, | ||
+ | {{SubtiWiki regulon|[[SigW regulon]]}} | ||
− | + | =The gene= | |
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− | = | + | === Basic information === |
− | * [[ | + | * '''Locus tag:''' BSU34430 |
− | * [[ | + | |
− | * [[ | + | ===Phenotypes of a mutant === |
− | + | ||
− | * [[ | + | === Database entries === |
− | * [[ | + | |
− | * [[ | + | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pbpE-racX.html] |
− | * [[ | + | |
+ | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10391] | ||
+ | |||
+ | === Additional information=== | ||
+ | |||
+ | |||
+ | |||
+ | |||
+ | =The protein= | ||
+ | |||
+ | === Basic information/ Evolution === | ||
+ | |||
+ | * '''Catalyzed reaction/ biological activity:''' | ||
+ | |||
+ | * '''Protein family:''' aspartate/glutamate racemases family (according to Swiss-Prot) | ||
+ | |||
+ | * '''Paralogous protein(s):''' | ||
+ | |||
+ | === Extended information on the protein === | ||
+ | |||
+ | * '''Kinetic information:''' | ||
+ | |||
+ | * '''Domains:''' | ||
+ | |||
+ | * '''Modification:''' | ||
+ | |||
+ | * '''Cofactor(s):''' | ||
+ | |||
+ | * '''Effectors of protein activity:''' | ||
+ | |||
+ | * '''Interactions:''' | ||
+ | |||
+ | * '''Localization:''' | ||
+ | |||
+ | === Database entries === | ||
+ | |||
+ | * '''Structure:''' | ||
+ | |||
+ | * '''UniProt:''' [http://www.uniprot.org/uniprot/P32960 P32960] | ||
+ | |||
+ | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU34430] | ||
+ | |||
+ | * '''E.C. number:''' | ||
+ | |||
+ | === Additional information=== | ||
+ | |||
+ | =Expression and regulation= | ||
+ | * '''Operon:''' ''[[pbpE]]-[[racX]]'' {{PubMed|8491712}} | ||
+ | |||
+ | * '''[[Sigma factor]]:''' [[SigW]] {{PubMed|8491712,12207695}} | ||
+ | |||
+ | * '''Regulation:''' | ||
+ | ** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed] | ||
+ | ** induced by cell wall stress ([[SigW]]) {{PubMed|8491712,12207695}} | ||
+ | |||
+ | * '''Regulatory mechanism:''' | ||
+ | ** [[AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed] | ||
+ | |||
+ | * '''Additional information:''' | ||
+ | |||
+ | =Biological materials = | ||
+ | |||
+ | * '''Mutant:''' | ||
+ | |||
+ | * '''Expression vector:''' | ||
+ | |||
+ | * '''lacZ fusion:''' | ||
+ | |||
+ | * '''GFP fusion:''' | ||
+ | |||
+ | * '''two-hybrid system:''' | ||
+ | |||
+ | * '''Antibody:''' | ||
+ | |||
+ | =Labs working on this gene/protein= | ||
+ | |||
+ | =Your additional remarks= | ||
+ | |||
+ | =References= | ||
+ | |||
+ | <pubmed>8491712,19063962,9987136, 20431016,7592498, </pubmed> | ||
+ | |||
+ | [[Category:Protein-coding genes]] |
Revision as of 13:27, 8 December 2010
- Description: amino acid racemase, production of D-amino acids, control of biofilm formation
Gene name | racX |
Synonyms | |
Essential | no |
Product | amino acid racemase |
Function | control of biofilm formation |
MW, pI | 25 kDa, 5.396 |
Gene length, protein length | 681 bp, 227 aa |
Immediate neighbours | yveF, pbpE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
biofilm formation, cell envelope stress proteins (controlled by SigM, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P32960
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References