YhdA

• Description: similar to NADPH-dependent azobenzene FMN reductase
  
  

Gene name	yhdA
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	18 kDa, 6.508
Gene length, protein length	522 bp, 174 aa
Immediate neighbours	yhcZ, yhdB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU09340

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: azoreductase type 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2GSW

• UniProt: O07529

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yhcY-yhcZ-yhdA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism: LiaR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

K Ramanathan, V Shanthi, Rao Sethumadhavan
In silico identification of catalytic residues in azobenzene reductase from Bacillus subtilis and its docking studies with azo dyes.
Interdiscip Sci: 2009, 1(4);290-7
[PubMed:20640807] [WorldCat.org] [DOI] (P p)

Diana Wolf, Falk Kalamorz, Tina Wecke, Anna Juszczak, Ulrike Mäder, Georg Homuth, Sina Jordan, Janine Kirstein, Michael Hoppert, Birgit Voigt, Michael Hecker, Thorsten Mascher
In-depth profiling of the LiaR response of Bacillus subtilis.
J Bacteriol: 2010, 192(18);4680-93
[PubMed:20639339] [WorldCat.org] [DOI] (I p)

Sina Jordan, Anja Junker, John D Helmann, Thorsten Mascher
Regulation of LiaRS-dependent gene expression in bacillus subtilis: identification of inhibitor proteins, regulator binding sites, and target genes of a conserved cell envelope stress-sensing two-component system.
J Bacteriol: 2006, 188(14);5153-66
[PubMed:16816187] [WorldCat.org] [DOI] (P p)