Difference between revisions of "PyrG"

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* '''Description:''' CTP synthase (NH3, glutamine) <br/><br/>
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=[http://aduratutuz.co.cc Under Construction! Please Visit Reserve Page. Page Will Be Available Shortly]=
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* '''Description:''' CTP synthase (NH3, glutamine) &lt;br/>&lt;br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine biosynthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine biosynthesis
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/pyrimidines_metabolism.html Pyrimidines], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: &lt;br/>[http://subtiwiki.uni-goettingen.de/pathways/pyrimidines_metabolism.html Pyrimidines], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 59 kDa, 5.16   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 59 kDa, 5.16   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywjG]]'', ''[[rpoE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywjG]]'', ''[[rpoE]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15743&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&amp;#91;EMBLCDS:CAB15743&amp;#93;+-newId sequences] &lt;br/> (Barbe ''et al.'', 2009)'''
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:pyrG_context.gif]]
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|colspan="2" | '''Genetic context''' &lt;br/> [[Image:pyrG_context.gif]]
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  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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  &lt;div align="right"> &lt;small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]&lt;/small>&lt;/div>
 
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__TOC__
 
__TOC__
  
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<br/><br/><br/><br/><br/><br/>
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&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>
  
 
=The gene=
 
=The gene=
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
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* '''Catalyzed reaction/ biological activity:''' ATP + UTP + NH<sub>3</sub> = ADP + phosphate + CTP (according to Swiss-Prot)  
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* '''Catalyzed reaction/ biological activity:''' ATP + UTP + NH&lt;sub>3&lt;/sub> = ADP + phosphate + CTP (according to Swiss-Prot)  
  
 
* '''Protein family:''' CTP synthase family (according to Swiss-Prot)
 
* '''Protein family:''' CTP synthase family (according to Swiss-Prot)
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=References=
 
=References=
  
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<pubmed>8206849,17302819,15252202,11544212,1709162,12426364,17158658,2457578  </pubmed>
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&lt;pubmed>8206849,17302819,15252202,11544212,1709162,12426364,17158658,2457578  &lt;/pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 01:01, 24 November 2010

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  • Description: CTP synthase (NH3, glutamine) <br/><br/>
Gene name pyrG
Synonyms ctrA
Essential yes PubMed
Product CTP synthase (NH3, glutamine)
Function pyrimidine biosynthesis
Metabolic function and regulation of this protein in SubtiPathways: <br/>Pyrimidines, Nucleotides (regulation)
MW, pI 59 kDa, 5.16
Gene length, protein length 1605 bp, 535 aa
Immediate neighbours ywjG, rpoE
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> PyrG context.gif 
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

  • Locus tag: BSU37150

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + UTP + NH<sub>3</sub> = ADP + phosphate + CTP (according to Swiss-Prot)
  • Protein family: CTP synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1VCM (from Thermus thermophilus, 52% identity, 70% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
    • RNA switch: transcription (termination in the presence of cytidine nucleotides) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>8206849,17302819,15252202,11544212,1709162,12426364,17158658,2457578 </pubmed>

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