Difference between revisions of "T-box"

From SubtiWiki
Jump to: navigation, search
(Reviews on T-box regulation)
Line 55: Line 55:
  
 
<pubmed> 19258532,7527891, 11917026 ,8348614,17381302 10546897 19932103 </pubmed>
 
<pubmed> 19258532,7527891, 11917026 ,8348614,17381302 10546897 19932103 </pubmed>
 +
=See also:=
 +
* [[RNA switch]]
 +
 +
=Back to [[regulons]]=

Revision as of 21:38, 9 April 2011

The T-box element is an RNA switch that controls genes involved in amino acid metabolism.

In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.

Complete list of genes controlled by T-box elements

  • Induction by alanine limitation
  • Induction by aspartate limitation
  • Induction by histidine limitation
  • Induction by phenyalanine limitation
  • Induction by serine limitation
  • Induction by tyrosine limitation

Structure of a T-box ribowsitch

Melinda S Gerdeman, Tina M Henkin, Jennifer V Hines
Solution structure of the Bacillus subtilis T-box antiterminator RNA: seven nucleotide bulge characterized by stacking and flexibility.
J Mol Biol: 2003, 326(1);189-201
[PubMed:12547201] [WorldCat.org] [DOI] (P p)


Reviews on T-box regulation

See also:

Back to regulons