tyrS
168
tyrosyl-tRNA synthetase (major)
Locus
BSU_29670
Molecular weight
47.57 kDa
Isoelectric point
5.21
Function
translation
Product
tyrosyl-tRNA synthetase (major)
Essential
quasi
E.C.
6.1.1.1
Synonyms
tyrS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0162 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,036,603 3,037,871
Phenotypes of a mutant
The protein
Catalyzed reaction/ biological activity
ATP + L-tyrosine + tRNATyr --> AMP + diphosphate + H+ + L-tyrosyl-tRNATyr (according to UniProt)
Protein family
S4 RNA-binding domain superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
Class-I aminoacyl-tRNA synthetase family (according to UniProt)
S4 RNA-binding domain (aa 355-421) (according to UniProt)
Structure
3TS1 (PDB) (complex with tyrosyl adenylate intermediate, Geobacillus stearothermophilus)
1JH3 (PDB) (C-terminal domain, Geobacillus stearothermophilus)
Paralogous protein(s)
Additional information
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
References
Reviews
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Original Publications
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Time of last update: 2025-04-01 05:51:17
Author of last update: Jstuelk