YtrB

• Description: acetoin ABC transporter (ATP-binding protein)
  
  

Gene name	ytrB
Synonyms
Essential	no
Product	acetoin ABC transporter (ATP-binding protein)
Function	uptake of acetoin
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	33 kDa, 5.505
Gene length, protein length	876 bp, 292 aa
Immediate neighbours	ytrC, ytrA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU30450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: (YtrB-YtrE)-(YtrC-YtrD)-YtrF PubMed

• Localization: cell membrane (via YtrC-YtrD) PubMed

Database entries

• Structure:

• UniProt: O34641

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed early in the stationary phase PubMed
  • induced by cold shock (2-fold) PubMed

• Regulatory mechanism:
  • YtrA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Carsten L Beckering, Leif Steil, Michael H W Weber, Uwe Völker, Mohamed A Marahiel
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis.
J Bacteriol: 2002, 184(22);6395-402
[PubMed:12399512] [WorldCat.org] [DOI] (P p)

K I Yoshida, Y Fujita, S D Ehrlich
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis.
J Bacteriol: 2000, 182(19);5454-61
[PubMed:10986249] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)