AraR

• Description: repressor of the arabinose utilization genes
  
  

Gene name	araR
Synonyms	araC, yvbS
Essential	no
Product	transcriptional repressor (GntR family, LacI family)
Function	regulation of arabinose utilization (araABDLMNPQ-abfA) and of the araE/araR genes
MW, pI	43 kDa, 6.341
Gene length, protein length	1152 bp, 384 aa
Immediate neighbours	araE, yvbT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33970

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GntR family: N-terminal DNA-binding domain, LacI family: C-terminal effector-binding domain

• Paralogous protein(s):

Genes/ operons controlled by AraR

• Activated by AraR:
• Repressed by AraR: araA-araB-araD-araL-araM-araN-araP-araQ-abfA, araE, araR

Extended information on the protein

• Kinetic information:

• Domains:
  • N-terminal DNA-binding domain (GntR family)
  • C-terminal effector-binding domain (LacI family)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P96711

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: araR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by arabinose (AraR) PubMed

• Regulatory mechanism:
  • AraR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: