Difference between revisions of "MecA"

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(Original Publications)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[mecA]]''
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* '''Operon:''' ''[[mecA]]'' {{PubMed|8412687}}
  
* '''[[Sigma factor]]:''' [[SigA]]
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8412687}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 19:30, 28 September 2009

  • Description: negative regulator of competence, targets ComK to ClpC-ClpP degradation machine (in log Phase)

Gene name mecA
Synonyms
Essential no
Product adaptor protein
Function control of ComK degradation, regulation of competence
MW, pI 25 kDa, 4.209
Gene length, protein length 654 bp, 218 aa
Immediate neighbours yjbE, coiA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MecA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU11520

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: mecA family (according to Swiss-Prot)
  • Paralogous protein(s): YpbH

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications