Difference between revisions of "CmoJ"

From SubtiWiki
Jump to: navigation, search
Line 89: Line 89:
  
 
=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}}
  
* '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}}
 
 
* '''[[Sigma factor]]:''' [[SigA]]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CymR]]: transcription repression {{PubMed|16109943}}
 +
** [[YtlI]]: transcription activation {{PubMed|16109943}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
Line 120: Line 122:
 
=References=
 
=References=
  
<pubmed>16109943,, </pubmed>
+
<pubmed>16109943,15668000, 15272571</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 22:26, 18 December 2009

  • Description: similar to nitrilotriacetate monooxygenase

Gene name ytnJ
Synonyms
Essential no
Product unknown
Function unknown
MW, pI 49 kDa, 5.715
Gene length, protein length 1326 bp, 442 aa
Immediate neighbours ribR, ytnI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtnJ context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU29310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ntaA/snaA/soxA(dszA) monooxygenase family (according to Swiss-Prot)
  • Paralogous protein(s): YxeK

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1YW1 (complex with FMN), 1TVL
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Pierre Burguière, Juliette Fert, Isabelle Guillouard, Sandrine Auger, Antoine Danchin, Isabelle Martin-Verstraete
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism.
J Bacteriol: 2005, 187(17);6019-30
[PubMed:16109943] [WorldCat.org] [DOI] (P p)

Irina M Solovieva, Rimma A Kreneva, Lubov Errais Lopes, Daniel A Perumov
The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product.
FEMS Microbiol Lett: 2005, 243(1);51-8
[PubMed:15668000] [WorldCat.org] [DOI] (P p)

I M Solov'eva, R A Kreneva, L L Erraĭs, A S Mironov, D A Perumov
[Study of the mechanism for regulating ribR gene activity in Bacillus subtilis]. [Issledovanie mekhanizma reguliatsii aktivnosti gena ribR u Bacillus subtilis.]
Genetika: 2004, 40(5);716-20
[PubMed:15272571] [WorldCat.org] (P p)