Difference between revisions of "PhrE"

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* '''Description:''' phosphatase (RapE) regulator <br/><br/>
+
* '''Description:''' phosphatase ([[RapE]]) regulator <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase (RapE) regulator
+
|style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase ([[RapE]]) regulator
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
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* '''Operon:'''  
 
* '''Operon:'''  
 +
** ''[[rapE]]-[[phrE]]'' {{PubMed|11466295,10629174}}
 +
** ''[[phrE]]'' {{PubMed|11466295}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
 +
''[[phrE]]'': [[SigA]] {{PubMed|11466295}}, [[SigH]] {{PubMed|11466295}}
  
 
* '''Regulation:''' repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   
 
* '''Regulation:''' repressed by glucose (10-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]   
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=References=
 
=References=
  
<pubmed>12618455,12850135, </pubmed>
+
<pubmed>12618455,12850135,11466295,10629174 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:30, 25 November 2009

  • Description: phosphatase (RapE) regulator

Gene name phrE
Synonyms
Essential no
Product phosphatase (RapE) regulator
Function control of sporulation initiation
MW, pI 4 kDa, 8.863
Gene length, protein length 132 bp, 44 aa
Immediate neighbours rapE, yqzI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU25840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

phrE: SigA PubMed, SigH PubMed

  • Regulation: repressed by glucose (10-fold) (CcpA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References