Difference between revisions of "KduD"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[kduI]]-[[kduD]]'' {{PubMed|17322190}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|17322190}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced by galacturonate ([[KdgR]]) {{PubMed|17322190}} | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|17322190}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[KdgR]]: transcription repression {{PubMed|17322190}} | ||
| + | ** [[CcpA]]: transcription repression {{PubMed|17322190}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 20:34, 26 October 2009
- Description: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
| Gene name | kduD |
| Synonyms | |
| Essential | no |
| Product | |
| Function | utilization of galacturonic acid |
| MW, pI | 27 kDa, 6.498 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | kduI, ypvA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU22140
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH (according to Swiss-Prot)
- Protein family: phosphopentomutase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P50842
- KEGG entry: [2]
- E.C. number: 1.1.1.125
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jer-Sheng Lin, Gwo-Chyuan Shaw
Regulation of the kduID operon of Bacillus subtilis by the KdgR repressor and the ccpA gene: identification of two KdgR-binding sites within the kdgR-kduI intergenic region.
Microbiology (Reading): 2007, 153(Pt 3);701-710
[PubMed:17322190]
[WorldCat.org]
[DOI]
(P p)
