Difference between revisions of "DfrA"
| Line 82: | Line 82: | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1ZDR 1ZDR] (Geobacillus stearothermophilus) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1ZDR 1ZDR] (Geobacillus stearothermophilus) | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P11045 P11045] |
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21810] | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21810] | ||
Revision as of 13:14, 20 July 2009
- Description: dihydrofolate reductase
| Gene name | dfrA |
| Synonyms | tmp |
| Essential | yes PubMed |
| Product | dihydrofolate reductase |
| Function | biosynthesis of folate |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation), Folate | |
| MW, pI | 19 kDa, 5.219 |
| Gene length, protein length | 504 bp, 168 aa |
| Immediate neighbours | ypkP, thyB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU21810
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH (according to Swiss-Prot)
- Protein family: spmB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 1ZDR (Geobacillus stearothermophilus)
- UniProt: P11045
- KEGG entry: [2]
- E.C. number: 1.5.1.3
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
