Difference between revisions of "SivC"
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− | * '''Description:''' | + | * '''Description:''' inhibitor of entry into [[sporulation]] via [[KinB]] or [[KinC]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || inhibitor of [entry into [[sporulation]] |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of entry into [[sporulation]] via the [[phosphorelay]] |
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15960 sivC] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 8.607 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 8.607 | ||
Line 20: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsY]]'', ''[[ylxM]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsY]]'', ''[[ylxM]]'' | ||
|- | |- | ||
− | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15960 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15960 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15960 DNA_with_flanks] |
− | |||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ylqB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ylqB_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylqB_1671166_1671651_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ylqB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15960]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/> | ||
− | + | = [[Categories]] containing this gene/protein = | |
+ | {{SubtiWiki category|[[phosphorelay]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
+ | {{SubtiWiki regulon|[[AbrB regulon]]}}, | ||
+ | {{SubtiWiki regulon|[[SigD regulon]]}} | ||
=The gene= | =The gene= | ||
Line 36: | Line 48: | ||
=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Locus tag:''' BSU15960 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15960&redirect=T BSU15960] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ylqB.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ylqB.html] | ||
Line 47: | Line 60: | ||
=== Additional information=== | === Additional information=== | ||
− | |||
=The protein= | =The protein= | ||
Line 54: | Line 66: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
+ | ** inhibits [[KinB]] or [[KinC]] activity {{PubMed|23335417}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
Line 71: | Line 84: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
− | * '''Localization:''' extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] | + | * '''[[Localization]]:''' |
+ | ** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15960&redirect=T BSU15960] | ||
* '''Structure:''' | * '''Structure:''' | ||
− | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/O31737 O31737] |
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15960] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' | + | * '''Operon:''' ''sivC'' {{PubMed|15033535}} |
+ | |||
+ | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylqB_1671166_1671651_-1 sivC] {{PubMed|22383849}} | ||
− | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|15033535}} |
− | * '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | + | * '''Regulation:''' |
+ | ** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | ||
+ | ** repressed during logarithmic growth ([[AbrB]]) {{PubMed|18840696}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | + | ** [[AbrB]]: transcription repression {{PubMed|18840696}} | |
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
− | * '''Mutant:''' | + | * '''Mutant:''' |
+ | ** BKE15960 (''[[sivC]]''::''erm'', available in the BGSC and in [[Jörg Stülke]]'s lab) | ||
+ | ** GP1823(''[[sivC]]''::''erm'', available in [[Jörg Stülke]]'s lab) | ||
* '''Expression vector:''' | * '''Expression vector:''' | ||
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=References= | =References= | ||
− | + | <pubmed>18957862 12107147, 15033535 18840696 23335417 </pubmed> | |
− | + | ||
− | + | [[Category:Protein-coding genes]] |
Latest revision as of 08:03, 21 July 2015
- Description: inhibitor of entry into sporulation via KinB or KinC
Gene name | ylqB |
Synonyms | |
Essential | no |
Product | inhibitor of [entry into sporulation |
Function | control of entry into sporulation via the phosphorelay |
Gene expression levels in SubtiExpress: sivC | |
MW, pI | 17 kDa, 8.607 |
Gene length, protein length | 483 bp, 161 aa |
Immediate neighbours | ftsY, ylxM |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15960
Phenotypes of a mutant
Database entries
- BsubCyc: BSU15960
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
Database entries
- BsubCyc: BSU15960
- Structure:
- UniProt: O31737
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: sivC PubMed
Biological materials
- Mutant:
- BKE15960 (sivC::erm, available in the BGSC and in Jörg Stülke's lab)
- GP1823(sivC::erm, available in Jörg Stülke's lab)
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References