Difference between revisions of "RNA polymerase"
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===Other interaction partners=== | ===Other interaction partners=== | ||
* [[NusA]]: essential elongation factor | * [[NusA]]: essential elongation factor | ||
| + | * [[NusG]]: transcription elongation factor {{PubMed|36745813}} | ||
* [[GreA]]: resolves promoter proximal pausing of RNA polymerase {{PubMed|21515770}} | * [[GreA]]: resolves promoter proximal pausing of RNA polymerase {{PubMed|21515770}} | ||
* [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}} | * [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}} | ||
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==References== | ==References== | ||
===Reviews=== | ===Reviews=== | ||
| − | <pubmed> 18599813 7708009 18410247 19889534 19489723 18280161 21233849 22210308 23433801 23768203 24763425 25878038 26132790 26010401 16524917,28657884,29856930</pubmed> | + | <pubmed> 18599813 7708009 18410247 19889534 19489723 18280161 21233849 22210308 23433801 23768203 24763425 25878038 26132790 26010401 16524917,28657884,29856930 32920946</pubmed> |
===The structure of RNA polymerase=== | ===The structure of RNA polymerase=== | ||
| − | <pubmed> 12732296 12581657 11297923 19735077 26293966 | + | <pubmed> 12732296 12581657 11297923 19735077 26293966 28652344 36745813 |
</pubmed> | </pubmed> | ||
=== Important original publications === | === Important original publications === | ||
| − | <pubmed> 21350489 21515770 22333917,20817769,20724389,21710567 23761441 23875654 23771146 24789973 25961799 26400263 27622946 27977677 29454936 31548377 </pubmed> | + | <pubmed> 21350489 21515770 22333917,20817769,20724389,21710567 23761441 23875654 23771146 24789973 25961799 26400263 27622946 27977677 29454936 31548377 32848247 33243850,36972428, 37949068 </pubmed> |
Latest revision as of 17:54, 20 November 2023
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Contents
The enzyme responsible for transcription
- As an important difference as compared to the E. coli enzyme, the B. subtilis RNA polymerase has a strong preference for G as first nucleotides in transcripts PubMed
Components of the RNA polymerase
Core subunits
Sigma factors
- In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)
Small accessory subunits
Other interaction partners
- NusA: essential elongation factor
- NusG: transcription elongation factor PubMed
- GreA: resolves promoter proximal pausing of RNA polymerase PubMed
- CshA: DEAD-box RNA helicase PubMed
- PcrA: ATP-dependent DNA helicase PubMed
Temporary interaction partners
- Spx: transcription regulator, interacts with RpoA
- MgsR: transcription regulator orthologous to Spx, interacts with RpoA
- Btr: transcription activator PubMed
- YlyA: modulates SigG-dependent transcription PubMed
- Additional interaction partners of the RNA polymerase (no specific subunit specified)
Back to protein-protein interactions
References
Reviews
The structure of RNA polymerase
Important original publications
