Difference between revisions of "SivC"

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* '''Description:''' unknown <br/><br/>
+
* '''Description:''' inhibitor of entry into [[sporulation]] via [[KinB]] or [[KinC]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || inhibitor of [entry into [[sporulation]]
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of entry into [[sporulation]] via the [[phosphorelay]]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15960 sivC]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 8.607   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 8.607   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsY]]'', ''[[ylxM]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ftsY]]'', ''[[ylxM]]''
 
|-
 
|-
−
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13469&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15960 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15960 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15960 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylqB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylqB_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 +
|-
 +
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylqB_1671166_1671651_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ylqB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15960]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/>
  
−
<br/><br/>
+
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[phosphorelay]]}}
 +
 
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[AbrB regulon]]}},
 +
{{SubtiWiki regulon|[[SigD regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15960&redirect=T BSU15960]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ylqB.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ylqB.html]
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=== Additional information===
 
=== Additional information===
−
 
  
 
=The protein=
 
=The protein=
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** inhibits [[KinB]] or [[KinC]] activity {{PubMed|23335417}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
−
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''  
  
−
* '''Localization:''' secreted (according to Swiss-Prot),  extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
+
* '''[[Localization]]:'''  
 +
** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15960&redirect=T BSU15960]
  
 
* '''Structure:'''
 
* '''Structure:'''
  
−
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O31737 O31737]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/O31737 O31737]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15960]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15960]
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=Expression and regulation=
 
=Expression and regulation=
  
−
* '''Operon:'''  
+
* '''Operon:''' ''sivC'' {{PubMed|15033535}}
 +
 
 +
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylqB_1671166_1671651_-1 sivC] {{PubMed|22383849}}
  
−
* '''[[[[Sigma factor]]]]:'''  
+
* '''[[Sigma factor]]:''' [[SigD]] {{PubMed|15033535}}
  
−
* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]   
+
* '''Regulation:'''  
 +
** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]   
 +
** repressed during logarithmic growth ([[AbrB]]) {{PubMed|18840696}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
−
 
+
** [[AbrB]]: transcription repression {{PubMed|18840696}}
−
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
  
−
* '''Mutant:'''
+
* '''Mutant:'''  
 +
** BKE15960 (''[[sivC]]''::''erm'', available in the BGSC and in [[Jörg Stülke]]'s lab)
 +
** GP1823(''[[sivC]]''::''erm'', available in [[Jörg Stülke]]'s lab)
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''
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=References=
 
=References=
  
−
<pubmed>18957862 12107147, </pubmed>
+
<pubmed>18957862 12107147, 15033535 18840696 23335417 </pubmed>
 +
 
 +
[[Category:Protein-coding genes]]

Latest revision as of 08:03, 21 July 2015

Gene name ylqB
Synonyms
Essential no
Product inhibitor of [entry into sporulation
Function control of entry into sporulation via the phosphorelay
Gene expression levels in SubtiExpress: sivC
MW, pI 17 kDa, 8.607
Gene length, protein length 483 bp, 161 aa
Immediate neighbours ftsY, ylxM
Sequences Protein DNA DNA_with_flanks
Genetic context
YlqB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlqB expression.png















Categories containing this gene/protein

phosphorelay

This gene is a member of the following regulons

AbrB regulon, SigD regulon

The gene

Basic information

  • Locus tag: BSU15960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
    • repressed during logarithmic growth (AbrB) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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