Difference between revisions of "LicT"
(→Extended information on the protein: Added the domains and the phosphorylation sites) |
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* '''Domains:''' | * '''Domains:''' | ||
| + | ** N-terminal RNA binding domain [http://www.ncbi.nlm.nih.gov/pubmed/10610766?dopt=Abstract Pubmed] | ||
| + | ** 2xPRD (PTS regulation domains) [http://www.ncbi.nlm.nih.gov/pubmed/11447120?dopt=Abstract PubMed] | ||
| − | * '''Modification:''' | + | * '''Modification:''' |
| + | ** phosphorylation at His-100 in PRD-1 by phosphorylated [[BglP]], inhibits LicT antitermination activity | ||
| + | ** phosphorylation at His-207 and/or His-269 in PRD-2 by His-P-[[ptsH|HPr]] | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
Revision as of 13:07, 3 June 2009
- Description: transcriptional antiterminator of the bglPH operon
| Gene name | licT |
| Synonyms | |
| Essential | no |
| Product | transcriptional antiterminator (BglG family) |
| Function | required for substrate-dependent induction of bglPH |
| MW, pI | 32 kDa, 5.944 |
| Gene length, protein length | 831 bp, 277 aa |
| Immediate neighbours | bglS, yxiP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU39080
Phenotypes of a mutant
no expression of the bglP-bglH operon
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binding to the mRNAs of bglS and the bglP-bglH operon, causes transcription antitermination (in presence of salicin and absence of glucose)
- Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot) BglG family of antiterminators
Extended information on the protein
- Kinetic information:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Swiss prot entry: P39805
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Josef Deutscher, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Michael Hecker, Greifswald, Germany Homepage
Your additional remarks
References
Original description
Control of LicT activity
Structural analysis of LicT
LicT-RNA interaction
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
