Difference between revisions of "IolR"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[iolR]]-[[iolS]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed] |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed] |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced by inositol ([[IolR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[IolR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
| Line 113: | Line 115: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| + | |||
| + | * [[Yasutaro Fujita]], University of Fukuyama, Japan | ||
| + | * [[Ken-ichi Yoshida]], Kobe University, Japan | ||
=Your additional remarks= | =Your additional remarks= | ||
Revision as of 17:33, 1 June 2009
- Description: transcriptional repressor of the iol operon
| Gene name | iolR |
| Synonyms | |
| Essential | no |
| Product | transcriptional repressor |
| Function | regulation of myo-inositol catabolism |
| MW, pI | 28 kDa, 6.331 |
| Gene length, protein length | 753 bp, 251 aa |
| Immediate neighbours | iolA, iolS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: inducer: 2-deoxy-5-keto-D-gluconic acid-6-phosphate
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P46337
- KEGG entry: BSU39770
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Yasutaro Fujita, University of Fukuyama, Japan
- Ken-ichi Yoshida, Kobe University, Japan
Your additional remarks
References
- Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y. (2008) myo-Inositol catabolism in Bacillus subtilis. J Biol Chem. Apr 18;283(16): 10415-24. PubMed
