Difference between revisions of "GntR"
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* '''Regulation:''' | * '''Regulation:''' | ||
** induced by gluconate ([[GntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/3020045 PubMed] | ** induced by gluconate ([[GntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/3020045 PubMed] | ||
| − | ** repressed by glucose ([[CcpA]]) | + | ** repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8370661 PubMed] |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[GntR]]: transcription repression | + | ** [[GntR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/3020045 PubMed] |
| − | ** [[CcpA]]: transcription repression | + | ** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed] |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 14:56, 30 May 2009
- Description: transcriptional repressor of the gluconate operon
| Gene name | gntR |
| Synonyms | |
| Essential | no |
| Product | transcriptional repressor of the gluconate operon |
| Function | regulation of gluconate utilization |
| MW, pI | 28 kDa, 5.26 |
| Gene length, protein length | 729 bp, 243 aa |
| Immediate neighbours | yxaA, gntK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: gluconate acts as molecular inducer
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P10585
- KEGG entry: BSU40050
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Yoshida K, Miwa Y, Ohmori H, Fujita Y. (1995) Analysis of an insertional operator mutation (gntOi) that affects the expression level of the Bacillus subtilis gnt operon, and characterization of gntOi suppressor mutations. Mol Gen Genet. Sep 20;248(5): 583-91. PubMed
- Fujita Y, Fujita T, Miwa Y, Nihashi J, Aratani Y. (1986) Organization and transcription of the gluconate operon, gnt, of Bacillus subtilis. J Biol Chem. Oct 15;261(29): 13744-53. PubMed
- Reizer A., Deutscher J., Saier M.H. Jr., Reizer J. (1991) Analysis of the gluconate (gnt) operon of Bacillus subtilis. Mol. Microbiol. 5: 1081-1089. PubMed
