Difference between revisions of "T-box"
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| − | The T-box element is | + | The T-box element is an [[RNA switch]] that controls genes involved in amino acid metabolism. |
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid. | In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid. | ||
Revision as of 20:30, 27 May 2009
The T-box element is an RNA switch that controls genes involved in amino acid metabolism.
In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.
Genes controlled by T-box elements
- Induction by alanine limitation
- Induction by isoleucine limitation
- Induction by leucine limitation
- Induction by serine limitation
- Induction by valine limitation
Reviews on T-box regulation
