YlnE

• Description: probably siroheme ferrochelatase
  
  

Gene name	ylnE
Synonyms
Essential	no
Product	probably siroheme ferrochelatase
Function	siroheme biosynthesis , sulfite reduction
MW, pI	28 kDa, 6.063
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	ylnD, ylnF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Siroheme + 2 H⁺ = sirohydrochlorin + Fe²⁺ (according to Swiss-Prot)

• Protein family: SirB subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: O34632

• KEGG entry: BSU15620

• E.C. number:

Expression and regulation

• Operon: cysH-cysP-sat-cysC-ylnD-ylnE-ylnF

• Sigma factor: SigA

• Regulation: repressed by casamino acids PubMed, repressed in the presence of cysteine (CymR)

• Regulatory mechanism: CymR: transcription repression, S-box Element: transcriptional antitermination

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed