Difference between revisions of "GlvR"

From SubtiWiki
Jump to: navigation, search
Line 93: Line 93:
 
* '''Sigma factor:''' [[SigA]]
 
* '''Sigma factor:''' [[SigA]]
  
* '''Regulation:''' repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
+
* '''Regulation:''' repressed by glucose ([[CcpA]])
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
Line 119: Line 119:
 
=References=
 
=References=
  
# Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in ''Bacillus subtilis'': regulation of the central metabolic pathways. ''Metab Eng.'' '''5:''' 133-149 [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
+
# Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in ''Bacillus subtilis'': regulation of the central metabolic pathways. ''Metab Eng.'' '''5:''' 133-149  
 
# Yamamoto H, Serizawa M, Thompson J, Sekiguchi J.(2001) Regulation of the ''glv'' operon in ''Bacillus subtilis'': YfiA (GlvR) is a positive regulator of the operon that is repressed through CcpA and cre. ''J Bacteriol.'' '''183:''' 5110-5121. [http://www.ncbi.nlm.nih.gov/sites/entrez/11489864 PubMed]
 
# Yamamoto H, Serizawa M, Thompson J, Sekiguchi J.(2001) Regulation of the ''glv'' operon in ''Bacillus subtilis'': YfiA (GlvR) is a positive regulator of the operon that is repressed through CcpA and cre. ''J Bacteriol.'' '''183:''' 5110-5121. [http://www.ncbi.nlm.nih.gov/sites/entrez/11489864 PubMed]

Revision as of 23:26, 2 April 2009

  • Description: transcriptional activator of maltose utilization

Gene name glvR
Synonyms yfiA
Essential no
Product transcriptional activator
Function regulation of maltose utilization
MW, pI 29 kDa, 5.446
Gene length, protein length 762 bp, 254 aa
Immediate neighbours malA, malP
Gene sequence (+200bp) Protein sequence
Genetic context
YfiA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149
  2. Yamamoto H, Serizawa M, Thompson J, Sekiguchi J.(2001) Regulation of the glv operon in Bacillus subtilis: YfiA (GlvR) is a positive regulator of the operon that is repressed through CcpA and cre. J Bacteriol. 183: 5110-5121. PubMed