DNA replication

Parent categories	3. Information processing 3.1. Genetics
Neighbouring categories	3.1.1. DNA replication 3.1.2. DNA condensation/ segregation 3.1.3. DNA restriction/ modification 3.1.4. DNA repair/ recombination 3.1.5. Genetic competence 3.1.6. Genetics/ other
Related categories	Replisome Primosome cell division
Overview on the categories (Excel file) All genes and their categories (Excel file)

• cell division and DNA replication are interlinked with each other, a block in either cell division or DNA replication results in inhibition of the other PubMed

Labs working on DNA replication

• Philippe Noirot
• Laurent Janniere

Genes in this functional category

• dnaA
• dnaB
• dnaC
• dnaD
• dnaE
• dnaG
• dnaI
• dnaN
• dnaX
• holA
• holB
• ligA
• ligB
• polC
• priA
• recD2
• rnhB
• rtp
• sirA
• ssbA
• ssbB
• topB
• xtmA
• xtmB
• yabA

Additional candidates (based on similarity)

• yorI
• yorL
• ypcP
• ypdQ

Important publications

Isabella V Hajduk, Christopher D A Rodrigues, Elizabeth J Harry
Connecting the dots of the bacterial cell cycle: Coordinating chromosome replication and segregation with cell division.
Semin Cell Dev Biol: 2016, 53;2-9
[PubMed:26706151] [WorldCat.org] [DOI] (I p)

Thomas R Beattie, Rodrigo Reyes-Lamothe
A Replisome's journey through the bacterial chromosome.
Front Microbiol: 2015, 6;562
[PubMed:26097470] [WorldCat.org] [DOI] (P e)

Heath Murray, Alan Koh
Multiple regulatory systems coordinate DNA replication with cell growth in Bacillus subtilis.
PLoS Genet: 2014, 10(10);e1004731
[PubMed:25340815] [WorldCat.org] [DOI] (I e)

Heidi A Arjes, Allison Kriel, Nohemy A Sorto, Jared T Shaw, Jue D Wang, Petra Anne Levin
Failsafe mechanisms couple division and DNA replication in bacteria.
Curr Biol: 2014, 24(18);2149-2155
[PubMed:25176632] [WorldCat.org] [DOI] (I p)

Nobuaki Kono, Kazuharu Arakawa, Mitsuru Sato, Hirofumi Yoshikawa, Masaru Tomita, Mitsuhiro Itaya
Undesigned selection for replication termination of bacterial chromosomes.
J Mol Biol: 2014, 426(16);2918-27
[PubMed:24946150] [WorldCat.org] [DOI] (I p)

Marcin Wolański, Dagmara Jakimowicz, Jolanta Zakrzewska-Czerwińska
Fifty years after the replicon hypothesis: cell-specific master regulators as new players in chromosome replication control.
J Bacteriol: 2014, 196(16);2901-11
[PubMed:24914187] [WorldCat.org] [DOI] (I p)

Geoffrey S Briggs, Wiep Klaas Smits, Panos Soultanas
Chromosomal replication initiation machinery of low-G+C-content Firmicutes.
J Bacteriol: 2012, 194(19);5162-70
[PubMed:22797751] [WorldCat.org] [DOI] (I p)

Charles S McHenry
DNA replicases from a bacterial perspective.
Annu Rev Biochem: 2011, 80;403-36
[PubMed:21675919] [WorldCat.org] [DOI] (I p)

Houra Merrikh, Cristina Machón, William H Grainger, Alan D Grossman, Panos Soultanas
Co-directional replication-transcription conflicts lead to replication restart.
Nature: 2011, 470(7335);554-7
[PubMed:21350489] [WorldCat.org] [DOI] (I p)

Alicia Bravo, Gemma Serrano-Heras, Margarita Salas
Compartmentalization of prokaryotic DNA replication.
FEMS Microbiol Rev: 2005, 29(1);25-47
[PubMed:15652974] [WorldCat.org] [DOI] (P p)