yorL

yorL
168

similar to DNA polymerase III (alpha subunit)

Locus
BSU_20340
Molecular weight
150.31 kDa
Isoelectric point
5.94
Protein length
1305 aaSequenceBlast
Gene length
3918 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
E.C.
2.7.7.7
Synonyms
yorL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0587 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,175,596  2,179,513
The protein
Catalyzed reaction/ biological activity
Deoxynucleoside triphosphate + DNA(n) --> diphosphate + DNA(n+1) (according to UniProt)
Protein family
DNA polymerase type-C family (with PolC and DnaE, according to UniProt)
Structure
3E0D (PDB) (from Thermus aquaticus, corresponds to aa 4 ... 1010 of YorL, 28% identity) PubMed
O31902 (AlphaFold)
Biological materials
Mutant
BKE20340 (yorL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACATCCTATCAACTTTTCTC,  downstream forward: _UP4_TAAATCTTAACTGATATAGG
BKK20340 (yorL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACATCCTATCAACTTTTCTC,  downstream forward: _UP4_TAAATCTTAACTGATATAGG
References
Research papers
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Time of last update: 2025-04-03 16:35:09

Author of last update: Melvin.boenninger