Ribosome

Most genes encoding ribosomal proteins are essential and many ribosomal proteins belong to the small set of universally conserved proteins.

Structure of the ribosome

• EMD-6306 (MifM-stalled ribosome complex) PubMed
• 3J9W (MifM-stalled ribosome complex) PubMed

Proteins of the large subunit

• L1
• L2
• L3
• L4
• L5
• L6
• L9
• L10
• L11
• L12
• L13
• L14
• L15
• L16
• L17
• L18
• L19
• L20
• L21
• L22
• L23
• L24
• L27
• L28
• L29
• L30
• L31
• L32
• L33a
• L33b
• L34
• L35
• L36

Proteins of the small subunit

• S2
• S3
• S4
• S5
• S6
• S7
• S8
• S9
• S10
• S11
• S12
• S13
• S14
• S15
• S16
• S17
• S18
• S19
• S20
• S21

Proteins that are part of the ribosome only under specific conditions

• Ctc: present in the large subunit under stress conditions
• RpmGC: replaces L33 under conditions of zinc limitation
• YbxF: L7 family, associated to the ribosome during logarithmic growth
• YhzA: replaces L31 under conditions of zinc limitation
• YtiA: replaces S14 under conditions of zinc limitation

Proteins that are similar to ribosomal proteins

• YfjL
• YlxQ
• YpfD

Related pages

• 5S rRNA
• 16S rRNA
• 23S rRNA
• translation

Reviews on ribosome structure and function

Ningning Li, Yuling Chen, Qiang Guo, Yixiao Zhang, Yi Yuan, Chengying Ma, Haiteng Deng, Jianlin Lei, Ning Gao
Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit.
Nucleic Acids Res: 2013, 41(14);7073-83
[PubMed:23700310] [WorldCat.org] [DOI] (I p)

Katelyn McGary, Evgeny Nudler
RNA polymerase and the ribosome: the close relationship.
Curr Opin Microbiol: 2013, 16(2);112-7
[PubMed:23433801] [WorldCat.org] [DOI] (I p)

Edward Ki Yun Leung, Nikolai Suslov, Nicole Tuttle, Raghuvir Sengupta, Joseph Anthony Piccirilli
The mechanism of peptidyl transfer catalysis by the ribosome.
Annu Rev Biochem: 2011, 80;527-55
[PubMed:21548786] [WorldCat.org] [DOI] (I p)

Zahra Shajani, Michael T Sykes, James R Williamson
Assembly of bacterial ribosomes.
Annu Rev Biochem: 2011, 80;501-26
[PubMed:21529161] [WorldCat.org] [DOI] (I p)

Sotaro Uemura, Colin Echeverría Aitken, Jonas Korlach, Benjamin A Flusberg, Stephen W Turner, Joseph D Puglisi
Real-time tRNA transit on single translating ribosomes at codon resolution.
Nature: 2010, 464(7291);1012-7
[PubMed:20393556] [WorldCat.org] [DOI] (I p)

T Martin Schmeing, V Ramakrishnan
What recent ribosome structures have revealed about the mechanism of translation.
Nature: 2009, 461(7268);1234-42
[PubMed:19838167] [WorldCat.org] [DOI] (I p)

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Veysel Berk, Jamie H D Cate
Insights into protein biosynthesis from structures of bacterial ribosomes.
Curr Opin Struct Biol: 2007, 17(3);302-9
[PubMed:17574829] [WorldCat.org] [DOI] (P p)

Andrei Korostelev, Sergei Trakhanov, Martin Laurberg, Harry F Noller
Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements.
Cell: 2006, 126(6);1065-77
[PubMed:16962654] [WorldCat.org] [DOI] (P p)

Maria Selmer, Christine M Dunham, Frank V Murphy, Albert Weixlbaumer, Sabine Petry, Ann C Kelley, John R Weir, V Ramakrishnan
Structure of the 70S ribosome complexed with mRNA and tRNA.
Science: 2006, 313(5795);1935-42
[PubMed:16959973] [WorldCat.org] [DOI] (I p)

Ada Yonath
High-resolution structures of large ribosomal subunits from mesophilic eubacteria and halophilic archaea at various functional States.
Curr Protein Pept Sci: 2002, 3(1);67-78
[PubMed:12370012] [WorldCat.org] [DOI] (P p)