Difference between revisions of "SwrAA/1"

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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** [[SwrA]]-[[DegU]] (N-terminal domain) {{PubMed|22496484}}
+
** [[SwrA]]-[[DegU]]-P (N-terminal domain) {{PubMed|24386445,22496484}}
  
 
* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
 
* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
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==Reviews==
 
==Reviews==
 
<pubmed>20735481 22092493 </pubmed>
 
<pubmed>20735481 22092493 </pubmed>
 
 
==Original publications==
 
==Original publications==
<pubmed>16091050 22773650 16357223,19389763,16030230,18567663,15066026 22496484 19389763 19749039 21278284 21602220,22329926,23190039</pubmed>
+
<pubmed>16091050 22773650 16357223,19389763,16030230,18567663,15066026 22496484 19389763 19749039 21278284 21602220,22329926,23190039 24386445 </pubmed>
 
[[Category:Pseudogenes]]
 
[[Category:Pseudogenes]]

Revision as of 14:46, 29 December 2014

  • Description: control of DegU activity, enhances sigD transcription, controls the number of flagellar basal bodies, inactive pseudogene in strain 168

Gene name swrAA/1
Synonyms yvzD, swrAA, ifm
Essential no
Product swarming motility protein
Function control of DegU activity
Gene expression levels in SubtiExpress: swrAA/1
Interactions involving this protein in SubtInteract: SwrA
MW, pI - , -
Gene length, protein length 336 bp, -
Immediate neighbours minJ, swrAA/2
Gene sequence (+200bp) Protein sequence
Genetic context
YvzD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
1 expression.png















Categories containing this gene/protein

biofilm formation, motility and chemotaxis, transcription factors and their control, pseudogenes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • This protein is functional in undomesticated strains of B.subtilis but not in laboratory strains, such as 168, because of a frameshift mutation. Therefore laboratory strains of B.subtilis are unable to swarm.
  • The frameshift in strain 168 is caused by a single insertion of an adenine in the codon for Tyr-12 which leads to the premature truncation of the protein in residue 13. In addition, the C-terminal section of swrAA was predicted to be an ORF (yvzD) by the genome project.
  • Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • interacts with the N-terminal domain of DegU to control the activity of DegU PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications