Difference between revisions of "PhoD"

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* '''Modification:'''
 
* '''Modification:'''
  
* '''[[Cofactors]]:'''
+
* '''[[Cofactors]]:'''  
 +
** one Fe and two Ca {{PubMed|25217636}}
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02620&redirect=T BSU02620]
 
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02620&redirect=T BSU02620]
  
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=2YEQ 2YEQ]
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=2YEQ 2YEQ] {{PubMed|25217636}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P42251 P42251]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P42251 P42251]

Revision as of 08:21, 19 September 2014

  • Description: phosphodiesterase/alkaline phosphatase

Gene name phoD
Synonyms ycbS
Essential no
Product phosphodiesterase/alkaline phosphatase
Function aquisition of phosphate upon phosphoate starvation
Gene expression levels in SubtiExpress: phoD
Interactions involving this protein in SubtInteract: PhoD
Metabolic function and regulation of this protein in SubtiPathways:
PhoD
MW, pI 62 kDa, 8.394
Gene length, protein length 1668 bp, 556 aa
Immediate neighbours yczK, tatAD
Sequences Protein DNA DNA_with_flanks
Genetic context
PhoD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhoD expression.png















Categories containing this gene/protein

phosphate metabolism

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU02620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A phosphate monoester + H2O = an alcohol + phosphate (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Oscar Kuipers, University of Groningen, The Netherlands Homepage

Your additional remarks

References

Reviews

Original publications