Difference between revisions of "ComC"

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(Original publications)
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28070&redirect=T BSU28070]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comC.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comC.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28070&redirect=T BSU28070]
  
 
* '''Structure:'''
 
* '''Structure:'''

Revision as of 14:24, 2 April 2014

Gene name comC
Synonyms
Essential no
Product processing protease
Function genetic competence
Gene expression levels in SubtiExpress: comC
Interactions involving this protein in SubtInteract: ComC
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 26 kDa, 9.843
Gene length, protein length 744 bp, 248 aa
Immediate neighbours spoIIB, folC
Sequences Protein DNA DNA_with_flanks
Genetic context
ComC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComC expression.png















Categories containing this gene/protein

genetic competence, protein secretion, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU28070

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • processing and translocation of ComGC, ComGD, ComGE and ComGG PubMed
    • Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)
  • Protein family: peptidase A24 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications