NadR

• Description: transcriptional repressor of genes involved in NAD biosynthesis
  
  

Gene name	nadR
Synonyms	yrxA
Essential	no
Product	transcriptional repressor
Function	regulation of NAD biosynthesis
Gene expression levels in SubtiExpress: nadR
MW, pI	19 kDa, 5.759
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	nifS, pheA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors, transcription factors and their control

This gene is a member of the following regulons

NadR regulon

The NadR regulon:

• nadB-nadC-nadA, nadR-nifS, niaP

The gene

Basic information

• Locus tag: BSU27890

Database entries

• BsubCyc: BSU27890

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU27890

• Structure:

• UniProt: P39667

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: nifS-nadR PubMed

• Expression browser: nadR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of nicotinic acid (NadR) PubMed

• Regulatory mechanism:
  • NadR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage