PspA

• Description: phage shock protein A homolog
  
  

Gene name	pspA
Synonyms	ydjF
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: pspA
MW, pI	24 kDa, 5.775
Gene length, protein length	681 bp, 227 aa
Immediate neighbours	fruC, ydjG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

AbrB regulon, SigW regulon

The gene

Basic information

• Locus tag: BSU06180

Phenotypes of a mutant

• more sensitive to nisin PubMed

Database entries

• BsubCyc: BSU06180

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: pspA/IM30 family (according to Swiss-Prot)

• Paralogous protein(s): LiaH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane protein

Database entries

• BsubCyc: BSU06180

• Structure:

• UniProt: P54617

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pspA-ydjG-ydjH-ydjI PubMed

• Expression browser: pspA PubMed

• Sigma factor: SigW PubMed

• Regulation:
  • induced by alkaline shock (SigW) PubMed
  • repressed during logarithmic phase (AbrB) PubMed
  • induced by antibiotics interacting with the cytoplasmic membrane PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: