Difference between revisions of "DapG"
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16760 dapG] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16760 dapG] | ||
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− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=dapG dapG]''' |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.709 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.709 |
Revision as of 10:49, 7 January 2014
- Description: aspartokinase I (alpha and beta subunits)
Gene name | dapG |
Synonyms | lssD |
Essential | no |
Product | aspartokinase I (alpha and beta subunits) |
Function | biosynthesis of lysine and peptidoglycan |
Gene expression levels in SubtiExpress: dapG | |
Metabolic function and regulation of this protein in SubtiPathways: dapG | |
MW, pI | 42 kDa, 5.709 |
Gene length, protein length | 1212 bp, 404 aa |
Immediate neighbours | asd, dapA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-aspartate = ADP + 4-phospho-L-aspartate (according to Swiss-Prot)
- Protein family: aspartokinase family (according to Swiss-Prot)
- Paralogous protein(s): LysC
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity: inhibited by diaminopimelic acid PubMed
Database entries
- Structure:
- UniProt: Q04795
- KEGG entry: [3]
- E.C. number: 2.7.2.4
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Chien-Chi Lo, Carol A Bonner, Gary Xie, Mark D'Souza, Roy A Jensen
Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways.
Microbiol Mol Biol Rev: 2009, 73(4);594-651
[PubMed:19946135]
[WorldCat.org]
[DOI]
(I p)
Original publications