Difference between revisions of "RpoY"
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=== Additional information=== | === Additional information=== | ||
The protein is sometimes annotated as omega1 subunit of [[RNA polymerase]], however, there is no experimental evidence in support of this ("it is unrelated in sequence to ω/Rpb6 from the eubacteria, archaea and eukaryotes, unpublished data suggests it does not bind at the same site as ω/Rpb6 subunits bind their cognate RNAPs, and therefore it is unlikely to function as a true ω subunit") {{PubMed|20724389}} | The protein is sometimes annotated as omega1 subunit of [[RNA polymerase]], however, there is no experimental evidence in support of this ("it is unrelated in sequence to ω/Rpb6 from the eubacteria, archaea and eukaryotes, unpublished data suggests it does not bind at the same site as ω/Rpb6 subunits bind their cognate RNAPs, and therefore it is unlikely to function as a true ω subunit") {{PubMed|20724389}} | ||
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=The protein= | =The protein= | ||
| Line 102: | Line 100: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[ykzG]]-[[rnjA]]'' {{PubMed|24187087}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykzG_1524791_1525000_-1 ykzG] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykzG_1524791_1525000_-1 ykzG] {{PubMed|22383849}} | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|24187087}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** translation of [[YkzG]] and [[RnjA]] is coupled, and this coupling is required for efficient expression of [[rnjA|RNase J1]] {{PubMed|24187087}} | ||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
| − | + | <pubmed>24187087 20724389</pubmed> | |
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:23, 13 November 2013
- Description: epsilon subunit of RNA polymerase
| Gene name | ykzG |
| Synonyms | |
| Essential | no |
| Product | epsilon subunit of RNA polymerase |
| Function | control of RNA polymerase activity |
| Gene expression levels in SubtiExpress: ykzG | |
| MW, pI | 8 kDa, 4.605 |
| Gene length, protein length | 207 bp, 69 aa |
| Immediate neighbours | rnjA, ykrA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14540
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein is sometimes annotated as omega1 subunit of RNA polymerase, however, there is no experimental evidence in support of this ("it is unrelated in sequence to ω/Rpb6 from the eubacteria, archaea and eukaryotes, unpublished data suggests it does not bind at the same site as ω/Rpb6 subunits bind their cognate RNAPs, and therefore it is unlikely to function as a true ω subunit") PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: UPF0356 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31718
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ailar Jamalli, Agnès Hébert, Léna Zig, Harald Putzer
Control of expression of the RNases J1 and J2 in Bacillus subtilis.
J Bacteriol: 2014, 196(2);318-24
[PubMed:24187087]
[WorldCat.org]
[DOI]
(I p)
Geoff P Doherty, Mark J Fogg, Anthony J Wilkinson, Peter J Lewis
Small subunits of RNA polymerase: localization, levels and implications for core enzyme composition.
Microbiology (Reading): 2010, 156(Pt 12);3532-3543
[PubMed:20724389]
[WorldCat.org]
[DOI]
(I p)
