NupC

• Description: pyrimidine nucleoside transport protein
  
  

Gene name	nupC
Synonyms
Essential	no
Product	pyrimidine nucleoside transport protein
Function	pyrimidine uptake
Gene expression levels in SubtiExpress: nupC
Metabolic function and regulation of this protein in SubtiPathways: Nucleoside catabolism, Nucleotides (regulation)
MW, pI	42 kDa, 9.316
Gene length, protein length	1179 bp, 393 aa
Immediate neighbours	pdp, dra
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of nucleotides, membrane proteins

This gene is a member of the following regulons

CcpA regulon, DeoR regulon

The gene

Basic information

• Locus tag: BSU39410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: SLC28A transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • membrane protein PubMed

Database entries

• Structure:

• UniProt: P39141

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dra-nupC-pdp PubMed

• Expression browser: nupC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • induced by deoxynucleotides (DeoR) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • DeoR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: