Difference between revisions of "PyrAB"
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pyrAB_1623736_1626951_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:pyrAB_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pyrAB_1623736_1626951_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:pyrAB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15520]] |
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Revision as of 13:18, 16 May 2013
- Description: carbamoyl-phosphate synthetase (catalytic subunit)
| Gene name | pyrAB |
| Synonyms | |
| Essential | no |
| Product | carbamoyl-phosphate synthetase (catalytic subunit) |
| Function | pyrimidine biosynthesis |
| Gene expression levels in SubtiExpress: pyrAB | |
| Metabolic function and regulation of this protein in SubtiPathways: Pyrimidines, Nucleotides (regulation) | |
| MW, pI | 117 kDa, 4.785 |
| Gene length, protein length | 3213 bp, 1071 aa |
| Immediate neighbours | pyrAA, pyrK |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate (according to Swiss-Prot)
- Protein family: carB family (according to Swiss-Prot)
- Paralogous protein(s): CarB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane PubMed
Database entries
- UniProt: P25994
- KEGG entry: [3]
- E.C. number: 6.3.5.5
Additional information
Expression and regulation
- Regulatory mechanism:
- PyrR: RNA switch, transcription termination/ antitermination (in the presence of uridine nucleotides: termination, in their absence: antitermination) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
