PucC

• Description: xanthine dehydrogenase
  
  

Gene name	pucC
Synonyms	yurD
Essential	no
Product	xanthine dehydrogenase
Function	purine utilization
Gene expression levels in SubtiExpress: pucC
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine catabolism, Nucleotides (regulation)
MW, pI	29 kDa, 8.576
Gene length, protein length	831 bp, 277 aa
Immediate neighbours	pucD, pucB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nucleotides

This gene is a member of the following regulons

PucR regulon

The gene

Basic information

• Locus tag: BSU32490

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Xanthine + NAD⁺ + H₂O = urate + NADH (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1JRO (from Rhodobacter capsulatus, 39% identity, 55% similarity) PubMed

• UniProt: O32145

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pucA-pucB-pucC-pucD-pucE PubMed

• Expression browser: pucC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced in the presence of purine nucleotides (effector: allantoin) (PucR) PubMed

• Regulatory mechanism:
  • PucR: transcription activaton PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: