KdgT

• Description: 2-keto-3-deoxygluconate permease
  
  

Gene name	kdgT
Synonyms
Essential	no
Product	2-keto-3-deoxygluconate permease
Function	utilization of galacturonic acid
Gene expression levels in SubtiExpress: kdgT
MW, pI	34 kDa, 8.935
Gene length, protein length	990 bp, 330 aa
Immediate neighbours	ypwA, kdgA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon, KdgR regulon, Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU22090

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sigma-70 factor family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P50847

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: kdgR-kdgK-kdgA-kdgT PubMed

• Expression browser: kdgT PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by galacturonate (KdgR) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • KdgR: transcription repression PubMed
  • CcpA: transcription repression PubMed

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Petar Pujic, Rozenn Dervyn, Alexei Sorokin, S Dusko Ehrlich
The kdgRKAT operon of Bacillus subtilis: detection of the transcript and regulation by the kdgR and ccpA genes.
Microbiology (Reading): 1998, 144 ( Pt 11);3111-3118
[PubMed:9846747] [WorldCat.org] [DOI] (P p)