Difference between revisions of "SigE"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIGA]]'', ''[[sigG]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIGA]]'', ''[[sigG]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 DNA_with_flanks]
 
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Revision as of 10:09, 14 May 2013

Gene name sigE
Synonyms spoIIGB
Essential no
Product RNA polymerase sporulation mother cell-specific
(early) sigma factor SigE
Function transcription of sporulation genes (early mother cell)
Gene expression levels in SubtiExpress: sigE
Interactions involving this protein in SubtInteract: SigE
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 27 kDa, 9.212
Gene length, protein length 717 bp, 239 aa
Immediate neighbours spoIIGA, sigG
Sequences Protein DNA DNA_with_flanks
Genetic context
SigE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SigE expression.png















Categories containing this gene/protein

transcription, sigma factors and their control

This gene is a member of the following regulons

SinR regulon, Spo0A regulon, Efp-dependent proteins

The SigE regulon

The gene

Basic information

  • Locus tag: BSU15320

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Protein family: sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Michiel J L de Hoon, Patrick Eichenberger, Dennis Vitkup
Hierarchical evolution of the bacterial sporulation network.
Curr Biol: 2010, 20(17);R735-45
[PubMed:20833318] [WorldCat.org] [DOI] (I p)

The SigE regulon

Original Publications

Additional publications: PubMed