Difference between revisions of "TuaD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichuronic acid
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichuronic acid
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU35580 tuaD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35580 tuaD]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/TuaD TuaD]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/TuaD TuaD]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tuaE]]'', ''[[tuaC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tuaE]]'', ''[[tuaC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15575&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35580 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:tuaD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:tuaD_context.gif]]

Revision as of 13:59, 13 May 2013

  • Description: UDP glucose 6-dehydrogenase

Gene name tuaD
Synonyms yvhD
Essential no
Product UDP glucose 6-dehydrogenase
Function biosynthesis of teichuronic acid
Gene expression levels in SubtiExpress: tuaD
Interactions involving this protein in SubtInteract: TuaD
MW, pI 49 kDa, 6.107
Gene length, protein length 1383 bp, 461 aa
Immediate neighbours tuaE, tuaC
Sequences Protein DNA Advanced_DNA
Genetic context
TuaD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TuaD expression.png
























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU35580

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH (according to Swiss-Prot)
  • Protein family: UDP-glucose/GDP-mannose dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Cofactor(s):
  • Effectors of protein activity: PtkA-dependent phosphorylation stimulates TuaD activity PubMed

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References