Difference between revisions of "SrtN"
| Line 13: | Line 13: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[AcsA]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[AcsA]] activity | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09650 srtN] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.134 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.134 | ||
| Line 21: | Line 21: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhdY]]'', ''[[yheN]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhdY]]'', ''[[yheN]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09650 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09650 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09650 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yhdZ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yhdZ_context.gif]] | ||
Revision as of 12:27, 13 May 2013
- Description: protein deacetylase for the control of AcsA activity
| Gene name | srtN |
| Synonyms | yhdZ |
| Essential | no |
| Product | NAD(+)-dependent AcsA deacetylase |
| Function | control of AcsA activity |
| Gene expression levels in SubtiExpress: srtN | |
| MW, pI | 27 kDa, 5.134 |
| Gene length, protein length | 741 bp, 247 aa |
| Immediate neighbours | yhdY, yheN |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09650
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NAD+ + an acetylprotein = nicotinamide + O-acetyl-ADP-ribose + a protein (according to Swiss-Prot) deacetylates (and thereby activates) AcsA (together with AcuC) PubMed
- Protein family: deacetylase sirtuin-type domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O07595
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP1210 (srtN::cat), available in Jörg Stülke's lab
- 1A888 ( srtN::spec), PubMed, available at BGSC
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
