Difference between revisions of "Ldh"
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|style="background:#ABCDEF;" align="center"|'''Function''' || overflow metabolism, fermentation | |style="background:#ABCDEF;" align="center"|'''Function''' || overflow metabolism, fermentation | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03050 ldh] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ldh Ldh] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Ldh Ldh] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[amyE]]'', ''[[lctP]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[amyE]]'', ''[[lctP]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03050 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03050 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03050 Advanced_DNA] |
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Revision as of 12:05, 13 May 2013
- Description: L-lactate dehydrogenase
| Gene name | ldh |
| Synonyms | lctE |
| Essential | no |
| Product | L-lactate dehydrogenase |
| Function | overflow metabolism, fermentation |
| Gene expression levels in SubtiExpress: ldh | |
| Interactions involving this protein in SubtInteract: Ldh | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 34 kDa, 5.394 |
| Gene length, protein length | 963 bp, 321 aa |
| Immediate neighbours | amyE, lctP |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
carbon core metabolism, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03050
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-lactate + NAD+ = pyruvate + NADH (according to Swiss-Prot)
- Protein family: LDH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Tyr-224 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- forms tetramers PubMed
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P13714
- KEGG entry: [3]
- E.C. number: 1.1.1.27
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional references: PubMed
