Difference between revisions of "AdaA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || adaptive response to alkylative DNA damage | |style="background:#ABCDEF;" align="center"|'''Function''' || adaptive response to alkylative DNA damage | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01810 adaA] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 9.185 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 9.185 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[alkA]]'', ''[[adaB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[alkA]]'', ''[[adaB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01810 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:adaA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:adaA_context.gif]] | ||
Revision as of 12:01, 13 May 2013
- Description: trigger enzyme: methylphosphotriester-DNA alkyltransferase/ transcriptional activator of the adaA-adaB operon
| Gene name | adaA |
| Synonyms | |
| Essential | no |
| Product | trigger enzyme: methylphosphotriester-DNA alkyltransferase/ transcriptional activator of the adaAB operon |
| Function | adaptive response to alkylative DNA damage |
| Gene expression levels in SubtiExpress: adaA | |
| MW, pI | 24 kDa, 9.185 |
| Gene length, protein length | 633 bp, 211 aa |
| Immediate neighbours | alkA, adaB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
DNA repair/ recombination, transcription factors and their control, trigger enzyme
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01810
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P19219
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
F Morohoshi, K Hayashi, N Munkata
Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon.
J Bacteriol: 1993, 175(18);6010-7
[PubMed:8376346]
[WorldCat.org]
[DOI]
(P p)
F Morohoshi, K Hayashi, N Munakata
Bacillus subtilis ada operon encodes two DNA alkyltransferases.
Nucleic Acids Res: 1990, 18(18);5473-80
[PubMed:2120677]
[WorldCat.org]
[DOI]
(P p)
