Difference between revisions of "MelA"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[CcpA regulon]]}} | |
=The gene= | =The gene= | ||
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[melA]]'' {{PubMed|9387221}} | + | * '''Operon:''' |
| + | ** ''[[msmR]]-[[msmE]]-[[amyD]]-[[amyC]]-[[melA]]'' {{PubMed|22383849}} | ||
| + | ** ''[[msmE]]-[[amyD]]-[[amyC]]-[[melA]]'' {{PubMed|22383849}} | ||
| + | ** ''[[melA]]'' {{PubMed|22383849,9387221}} | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=melA_3100881_3102179_1 melA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=melA_3100881_3102179_1 melA] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
| + | ** ''[[msmR]]'': [[SigA]] {{PubMed|22900538}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** [[MsmR]] | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|22900538}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CcpA]]: transcription repression {{PubMed|22900538}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed> 9387221 </pubmed> | + | <pubmed> 9387221 22383849 22900538</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:31, 23 August 2012
- Description: alpha-galactosidase
| Gene name | melA |
| Synonyms | |
| Essential | no |
| Product | alpha-galactosidase |
| Function | melibiose utilization |
| Gene expression levels in SubtiExpress: melA | |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 49 kDa, 5.84 |
| Gene length, protein length | 1296 bp, 432 aa |
| Immediate neighbours | amyC, ytwF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30300
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 4 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34645
- KEGG entry: [3]
- E.C. number: 3.2.1.22
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
