Difference between revisions of "FtsH"
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|colspan="2" | '''Genetic context''' <br/> [[Image:ftsH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ftsH_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ftsH_76984_78897_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ftsH_expression.png|500px]] | ||
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Revision as of 13:05, 8 August 2012
- Description: ATP-dependent metalloprotease
Gene name | ftsH |
Synonyms | |
Essential | no |
Product | ATP-dependent metalloprotease |
Function | cell division, sporulation initiation |
Gene expression levels in SubtiExpress: ftsH | |
Metabolic function and regulation of this protein in SubtiPathways: Phosphorelay, Stress | |
MW, pI | 70 kDa, 5.841 |
Gene length, protein length | 1911 bp, 637 aa |
Immediate neighbours | hprT, coaX |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell division, cell envelope stress proteins (controlled by SigM, V, W, X, Y), heat shock proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00690
Phenotypes of a mutant
strongly reduced sporulation frequency
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: degrades Spo0E and Spo0M, resulting in reduced sporulation frequency in a ftsH mutant PubMed
- Protein family:
- Paralogous protein(s): YjoB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- UniProt: P37476
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by heat shock (class III)
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References