Difference between revisions of "Fbp"
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|colspan="2" | '''Genetic context''' <br/> [[Image:fbp_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:fbp_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fbp_4128029_4130044_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:fbp_expression.png|500px]] | ||
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Revision as of 12:56, 23 April 2012
- Description: fructose-1,6-bisphosphatase, involved in gluconeogenesis
Gene name | fbp |
Synonyms | fdp, yydE |
Essential | no |
Product | fructose-1,6-bisphosphatase |
Function | gluconeogenesis |
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism, Sugar catabolism | |
MW, pI | 77 kDa, 5.601 |
Gene length, protein length | 2013 bp, 671 aa |
Immediate neighbours | yydF, yydD |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40190
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate (according to Swiss-Prot)
- Protein family: FBPase class 3 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q45597
- KEGG entry: [3]
- E.C. number: 3.1.3.11
Additional information
Expression and regulation
- Operon: fpb PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Y Fujita, K Yoshida, Y Miwa, N Yanai, E Nagakawa, Y Kasahara
Identification and expression of the Bacillus subtilis fructose-1, 6-bisphosphatase gene (fbp).
J Bacteriol: 1998, 180(16);4309-13
[PubMed:9696785]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, E Freese
Isolation and properties of a Bacillus subtilis mutant unable to produce fructose-bisphosphatase.
J Bacteriol: 1981, 145(2);760-7
[PubMed:6257649]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, E Freese
Purification and properties of fructose-1,6-bisphosphatase of Bacillus subtilis.
J Biol Chem: 1979, 254(12);5340-9
[PubMed:221467]
[WorldCat.org]
(P p)