Difference between revisions of "PsdR"
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* '''Operon:''' ''[[psdR]]-[[psdS]]-[[psdA]]-[[psdB]]'' {{PubMed|21078927}} | * '''Operon:''' ''[[psdR]]-[[psdS]]-[[psdA]]-[[psdB]]'' {{PubMed|21078927}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvcP_3567422_3568135_-1 psdR] {{PubMed|22383849}} |
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| + | * '''Sigma factor:''' [[SigA]] {{PubMed|21078927}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 07:12, 17 April 2012
- Description: two-component response regulator, induction of psdA-psdB in response to lipid II-binding lantibiotics, such as nisin and gallidermin
| Gene name | psdR |
| Synonyms | yvcP |
| Essential | no |
| Product | two-component response regulator |
| Function | resistance against toxic peptides |
| Interactions involving this protein in SubtInteract: PsdR | |
| MW, pI | 27 kDa, 4.676 |
| Gene length, protein length | 711 bp, 237 aa |
| Immediate neighbours | psdS, yvcN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins
This gene is a member of the following regulons
The PsdR regulon: psdA-psdB
The gene
Basic information
- Locus tag: BSU34720
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component response regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by PsdS on an Asp residue
- Cofactor(s):
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O06978
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
