FloA

• Description: resistence protein (against sublancin), accessory role in resistance to cefuroxime, second bacterial flottilin-like protein (in addition to FloT)
  
  

Gene name	yqfA
Synonyms
Essential	no
Product	resistence protein (against sublancin)
Function	resistance against sublancin
MW, pI	35 kDa, 4.917
Gene length, protein length	993 bp, 331 aa
Immediate neighbours	yqfB, yqeZ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

SigW regulon

The gene

Basic information

• Locus tag: BSU25380

Phenotypes of a mutant

• • a floT yqfA double mutant does not induce KinC-dependent biofilm formation upon addition of surfactin PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UPF0365 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • membrane PubMed
  • co-localizes with FloT in discrete foci in the membrane PubMed

Database entries

• Structure:

• UniProt: P54466

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yqeZ-yqfA-yqfB PubMed

• Sigma factor: SigW PubMed

• Regulation:
  • expressed under stress conditions (SigW) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed