Difference between revisions of "MtrB"

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(Extended information on the protein)
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
 +
** binding of tryptophan results RNA binding and thus in transcription termination
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** forms 11-mers
 
** [[MtrB|TRAP]]-[[RtpA]] {{PubMed|11557884}}
 
** [[MtrB|TRAP]]-[[RtpA]] {{PubMed|11557884}}
  
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<pubmed>19385727, 16285852, </pubmed>
 
<pubmed>19385727, 16285852, </pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed> 19033375, 17881743 10660627 10714985 12963367 14702295 16879415 17114058 17114263 11805104,7525975,10735881,15262953,14976255,8647825,18334255,10499579,7715723,8932308,11214184,15743934,7515880,9242649,7759487,15050822,14687568,9245598,9765233,11914485,15099736,7678334,8643393,15588817,16738132,1551827,17555767,7544009,11786553,11566976,2123343,11557884,12133840,16784236,10369778,7715723 10499579 11566976 7515880, 21097886 </pubmed>
+
<pubmed> 19033375, 17881743 10660627 10714985 12963367 14702295 16879415 17114058 17114263 11805104,7525975,10735881,15262953,14976255,8647825,18334255,10499579,7715723,8932308,11214184,15743934,7515880,9242649,7759487,15050822,14687568,9245598,9765233,11914485,15099736,7678334,8643393,15588817,16738132,1551827,17555767,7544009,11786553,11566976,2123343,11557884,12133840,16784236,10369778,7715723 10499579 11566976 7515880, 21097886 21984911 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:04, 11 October 2011

  • Description: tryptophan operon RNA-binding attenuation protein (TRAP), controls the RNA switch in front of genes involved in biosynthesis and acquisition of tryptophan

Gene name mtrB
Synonyms
Essential no
Product tryptophan operon RNA-binding attenuation protein (TRAP)
Function regulation of tryptophan biosynthesis
(and translation) attenuation in the trp operon;
repression of the folate operon
Interactions involving this protein in SubtInteract: TRAP
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp, Folate
MW, pI 8 kDa, 7.333
Gene length, protein length 225 bp, 75 aa
Immediate neighbours hepS, folE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MtrB context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, transcription factors and their control, RNA binding regulators

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: prpD family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes controlled by MtrB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • binding of tryptophan results RNA binding and thus in transcription termination

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications