Difference between revisions of "PutP"
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|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''putP'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ycgO '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
| Line 18: | Line 18: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1347 bp, 449 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1347 bp, 449 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[putC]]'', ''[[putR]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12116]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12116]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 34: | Line 34: | ||
{{SubtiWiki category|[[transporters/ other]]}}, | {{SubtiWiki category|[[transporters/ other]]}}, | ||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
| + | {{SubtiWiki category|[[utilization of amino acids]]}} | ||
{{SubtiWiki category|[[membrane proteins]]}} | {{SubtiWiki category|[[membrane proteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[PutR regulon]]}} | |
=The gene= | =The gene= | ||
| Line 46: | Line 47: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * no growth with proline as single source of carbon or nitrogen {{PubMed|21840319}} | ||
=== Database entries === | === Database entries === | ||
| Line 54: | Line 56: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 99: | Line 98: | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[putB]]-[[putC]]-[[putP]]'' {{PubMed|21840319}} | ||
| + | ** ''[[putP]]'' (internal promoter) {{PubMed|21840319}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[putB]]'': [[SigA]] {{PubMed|21840319}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in the presence of proline ([[PutR]]) {{PubMed|21840319}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[PutR]]: transcription activation {{PubMed|21840319}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 127: | Line 131: | ||
=References= | =References= | ||
| − | + | <pubmed> 21840319 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:51, 17 August 2011
- Description: high affinity proline permease
| Gene name | putP |
| Synonyms | ycgO |
| Essential | no |
| Product | high affinity proline permease |
| Function | proline uptake |
| MW, pI | 48 kDa, 8.619 |
| Gene length, protein length | 1347 bp, 449 aa |
| Immediate neighbours | putC, putR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transporters/ other, biosynthesis/ acquisition of amino acids, utilization of amino acids membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03220
Phenotypes of a mutant
- no growth with proline as single source of carbon or nitrogen PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): OpuE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P94392
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris R Belitsky
Indirect repression by Bacillus subtilis CodY via displacement of the activator of the proline utilization operon.
J Mol Biol: 2011, 413(2);321-36
[PubMed:21840319]
[WorldCat.org]
[DOI]
(I p)
